Modern day medical practice is highly dependent on the laboratory analysis of body fluids especially the blood. Biochemistry is perhaps the most fascinating subject as it deals with the chemical language of life. Biochemical analysis gives the scientific basis of the disease which is useful for its treatment and prognosis. Biochemistry holds a key position in the curriculum of dental sciences and is one of the basic principal science subjects for the first year professional dental students. A sound and comprehensive learning of biochemistry helps a dental student to understand medicine and pathology clearly and precisely. At the end of the first year training the students attain the ability for the biochemical analysis of body fluids. In Mar Baselios Dental College (MBDC), Biochemistry department is unique with experienced full time faculty. All the faculties have inquisitive attitude, determination, perseverance and keen observation sense along with intelligence and hard work. Our curriculum includes presentation, seminar and discussion on the subject .An understanding of modern biochemistry is impossible without an introduction to experimental methods for which MBDC has provided well equipped laboratory and clinical materials. Both foreign and Indian edition books are available in the departmental library. In addition to the BDS Programme students, we also give guidance to the MDS Programme and BSc Nursing students.